tag:blogger.com,1999:blog-2658003869927046449.post2514474084829813293..comments2021-09-06T23:41:31.894-04:00Comments on Kneeless Megafauna: The Postprandial ElephantGreghttp://www.blogger.com/profile/00966592489321207595noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-2658003869927046449.post-65548563338657382902013-01-24T23:12:41.010-05:002013-01-24T23:12:41.010-05:00Coconut oil is largely medium chain triglycerides ...Coconut oil is largely medium chain triglycerides which do not provoke a sharp rise in triglycerides. They would instead produce a large increase in blood ketones, which I did not measure. Coconut oil has been shown to permit LPS absorption, but it also reputedly has anti-inflammatory properties, so it is unclear which effect would dominate, or if there would be a complex interaction that depends on what other foods are consumed at the same time (e.g. does coconut oil, via LPS, worsen the postprandial response to other fats? Easy to test but I haven't done it).<br /><br />The data I showed in this post is probably not sufficient to identify the inflammatory response caused by the various fats, though I think it is clear that the macadamia nuts are absorbing most slowly (lower peak, longer tail vs. avocados). So I can't say from what I've shown above whether coconut oil is a good fat, though I suspect for other reasons that it probably is (subject to improper processing, contamination, etc.). I do generally prefer butter.<br /><br />I think the spicier / darker olive oils are probably best. Unfiltered will likely be higher in polyphenols which could be anti-inflammatory. It is important to make sure you are getting actual olive oil that has not been adulterated. I prefer the ones from California (e.g. California Olive Ranch).<br /><br />There is certainly some interaction between carbs and fats in terms of meal timing, but it is more complicated than just eating them at separate meals. I suspect there are possible priming and/or tolerance effects, as you would see, for example, with repeated LPS infusions. Insulin should drive triglycerides out of blood and into adipose tissue, so there may be a relative timing (e.g. carbs 1-2 hours after fat) that actually improves things. On the other hand, if the fat meal causes insulin resistance, this may be a really bad idea. Again not too hard to test but I haven't done these experiments. People who like to eat carbs are encouraged to try it and report what they discover.<br /><br />Baseline carb quantity in the diet seems to raise the postprandial inflammatory response to fats, at least in case of the sweet potatoes I was eating last year. Other carbs may not do that and I'm planning on trying it with white rice some time this year. Perhaps carbs are best consumed before the longest fast of the day (i.e. at night) in order to allow their aftereffects to dissipate so there is no interaction with subsequent fatty meals. No idea, but an accurate model may help in figuring it out, either directly or by suggesting informative experiments.<br /><br />Sorry if this entirely fails to answer your questions. I am suspicious of "intuitive conclusions", as you can see!Greghttps://www.blogger.com/profile/00966592489321207595noreply@blogger.comtag:blogger.com,1999:blog-2658003869927046449.post-57099398145149261362013-01-18T12:06:21.461-05:002013-01-18T12:06:21.461-05:00This is very impressive and way beyond my technica...This is very impressive and way beyond my technical and personal capabilities. As intuitive conclusions would you agree with:<br />Coconut oil is a good fat<br />Non-filtered olive oil preferred to filtered one<br />Eat your carbs and fats in separate meals<br /><br />ThanksMikihttps://www.blogger.com/profile/01336665212024168702noreply@blogger.com